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Corneal Epithelium

The outermost layer of the cornea, its renewal by limbal stem cells, and treatments for corneal surface disease.

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Differentiation Induction of Human Stem Cells for Corneal Epithelial Regeneration
Clinical
1 min read
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Differentiation Induction of Human Stem Cells for Corneal Epithelial Regeneration
Loss or severe damage of the corneal epithelium (the clear, outer surface of the eye) can cause vision loss. Donor tissue for direct corneal or limbal epithelial transplantation is limited, and allogeneic grafts carry a rejection risk. Researchers are developing ways to turn a patient’s own stem cells into corneal epithelial cells for transplantation. This review summarizes what works so far with human stem cells — especially mesenchymal stem/stromal cells (MSCs) and pluripotent stem cells (ESCs
Induced Pluripotent Stem Cells (iPSCs)Mesenchymal stem cellsCorneal EpitheliumLimbal Stem Cell Deficiency

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