Bone Marrow

This study confirms that long-term cryopreservation of bone marrow for up to 7.8 years does not negatively impact hematopoietic stem cell viability or engraftment success. Results indicate that early-stage marrow collection can effectively preserve stem cell quality before cumulative damage from chemotherapy or radiation occurs. This research supports the long-term storage of autologous bone marrow as a reliable option for future transplantation.

Recent research in gerontology shows that injecting young bone marrow into older mice can increase their remaining lifespan by up to 39%. While these findings highlight the exciting potential of regenerative medicine for life extension, further study is needed to determine how these biological mechanisms translate to human aging.

Intravenous transplantation of bone marrow-derived mononuclear cells (BMMCs) successfully improved cognitive function and prevented neurodegeneration in two different Alzheimer's disease mouse models.