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Orthopedic

Bone, joint, and musculoskeletal health including fractures, arthritis, and regenerative treatments for cartilage and connective tissue.

5 articles

Moving Beyond the Quick Fix: Why Your Future Health Depends on Regenerative Orthopedics
Blog
1 min read
Moving Beyond the Quick Fix: Why Your Future Health Depends on Regenerative Orthopedics
In the latest Future Proof with Forever Labs episode, Dr. Trevor Turner shares the latest on regenerative orthopedics at CartiNova. Discover how to move beyond pain management to genuine joint repair, securing lifelong mobility with banked stem cells and more.
CryopreservationOsteoarthritisPrecision MedicineOrthopedicJoint Restoration
AI generated image for: Study Finds Using Your Own Blood Reduces Delirium After Hip Surgery
Clinical
1 min read
Pubmed
Study Finds Using Your Own Blood Reduces Delirium After Hip Surgery
Using your own blood during surgery can help keep your mind clear and sharp while you recover. This study shows that using your own cells instead of a donor's reduces the risk of confusion and helps you heal faster.
Hip ArthroplastyPostoperative DeliriumAutologous TransfusionOrthopedic
Florida’s New Stem Cell Law: What It Signals for Physicians, Patients and the Future of Regenerative Medicine
Regulatory
1 min read
Medcitynews
Florida’s New Stem Cell Law: What It Signals for Physicians, Patients and the Future of Regenerative Medicine
Something important changed in Florida on July 1: the state passed a law (Senate Bill SB‑1768) that allows licensed physicians to offer certain stem cell treatments that are not yet FDA-approved — but only for specific uses (orthopedics, wound care, and pain management) and only if strict rules a...
Perinatal Stem CellsWound CareRegulatory ComplianceOrthopedic
AI generated image for: Viability and osteogenic potential of cryopreserved human bone marrow-derived mesenchymal cells
Clinical
1 min read
Tissue Eng
Viability and osteogenic potential of cryopreserved human bone marrow-derived mesenchymal cells
Human bone marrow-derived mesenchymal cells contain mesenchymal stem cells (MSCs), which are well known for their osteo/chondrogenic potential and can be used for bone reconstruction. This article reports the viability of cryopreserved human mesenchymal cells and a comparison of the osteogenic potential between noncryopreserved and cryopreserved human mesenchymal cells with MSC-like characteristics, derived from the bone marrow of 28 subjects. The viability of cryopreserved mesenchymal cells was approximately 90% regardless of the storage term (0.3 to 37 months). It is clear by fluorescence-activated cell sorter analysis that the cell surface antigens of both noncryopreserved and cryopreserved mesenchymal cells were negative for hematopoietic cell markers such as CD14, CD34, CD45, and HLA-DR but positive for mesenchymal characteristics such as CD29 and CD105. To monitor the osteogenic potential of the cells, such as alkaline phosphatase (ALP) activity and in vitro mineralization, a subculture was conducted in the presence of dexamethasone, ascorbic acid, and glycerophosphate. No difference in osteogenic potential was found between cells with or without cryopreservation treatment. In addition, cells undergoing long-term cryopreservation (about 3 years) maintained high osteogenic potential. In conclusion, cryopreserved as well as noncryopreserved human mesenchymal cells could be applied for bone regeneration in orthopedics.
Orthopedic

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