Stem Cell–Based Immunomodulation After Stroke: Effects on Brain Repair Processes
Stem cell-based approaches can induce poststroke recovery via mechanisms, such as neuronal replacement, promotion of angiogenesis, induction of brain plasticity, reduction of cell death, or immunomodulation.
Autologous mesenchymal stem cell transplantation in stroke patients
Changes in neurological deficits and improvements in function were compared between two groups for 1 year after symptom onset. Patients treated with autologous MSCs showed significant improvement in both cognition and mobility.